Priority List of Adverse events of special interest for
Nipah
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AESI: Thrombocytopenic Thrombosis Syndrome ²
Specific to vaccine: Adeno vectors
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023
AESI: Anaphylaxis
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Thrombocytopenia
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Acute aseptic arthritis
Specific to vaccine: VSV vector
Brighton Case Definition: Click to access
Brighton CD Companion Guide: End of 2023
AESI: Generalized convulsion
Specific to Nipah disease: 
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Aseptic meningitis
Specific to Nipah disease:
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Encephalitis
Specific to Nipah disease:
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Myelitis
Specific to Nipah disease:
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition:
Brighton CD Companion Guide: Click to access
AESI: Guillain Barré Syndrome
Specific to vaccine: Some vaccines¹
Brighton CD Companion Guide: Click to access
AESI: Acute Respiratory Distress Syndrome
Specific to Nipah disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
Body System | AESI | Specific to Nipah disease | Specific to | Brighton Case Definition | Brighton CD Companion Guide |
|---|---|---|---|---|---|
| Hematologic | Thrombocytopenic Thrombosis Syndrome | Adeno vectors | End of 2023 | End of 2023 | |
| Immunologic | Anaphylaxis | All vaccines | |||
| Thrombocytopenia | All vaccines | ||||
| Musculoskeletal | Acute aseptic arthritis | VSV vector | End of 2023 | ||
| Neurologic | Generalized convulsion | ✅ | All vaccines | ||
| Aseptic meningitis | ✅ | Live attenuated viral vaccine | |||
| Encephalitis | ✅ | Live attenuated viral vaccine | |||
| Myelitis | ✅ | Live attenuated viral vaccine | |||
| GBS | Some vaccines¹ | ||||
| Respiratory | ARDS | ✅ | |||
1 Some seasonal influenza vaccines; monovalent H1N1 pandemic vaccine; COVID-19 ChAdOx-1 S vaccine.
Learn more about methods and results of the creation of the Priority List of potential Adverse events of special interest relevant to Nipah vaccine trials HERE.
SEE ALL THE LISTS OF AESIs FOR THE CEPI PRIORITIZED PATHOGENS:
